Pharmacology & Efficacy Studies
General Biology & Efficacy Models
Conducting studies to determine how well a substance works. This includes a variety of in vitro and in vivo (animal) models across different therapeutic areas.
Inflammation & Pain Models
Investigating the effectiveness of compounds against inflammatory and pain conditions using models such as collagen-induced arthritis, DSS or acetic acid-induced colitis, psoriasis-like skin disease, excision wound healing, osteoarthritis, carrageenan-induced paw edema, and models for mechanical, thermal, cold hyperalgesia, and neuropathic pain (e.g., spinal nerve ligation, partial sciatic nerve ligation, etc).
Antipsychotic Activity Models
Assessing compounds for their potential to treat psychosis and related neurobehavioral disorders, using tests like the Novel Object Recognition Test, social interaction deficits, disruption of Conditioned Avoidance Response, restoration of pre-pulse inhibition (PPI), and various neurobehavioral assays.
Metabolic Disorders Models
Studying interventions for conditions like STZ-induced diabetes, diabetic neuropathy, hypothyroidism, and acute or chronic kidney diseases in rodent models.
Safety Pharmacology Models
Evaluating the potential adverse effects of substances on vital bodily functions (e.g., central nervous system, cardiovascular, respiratory) using tests like rota rod, grip strength, tail flick, hot plate, and non-invasive blood pressure recording.
Osteoporosis Models
Researching potential treatments for bone density loss using models such as ovariectomy-induced osteoporosis, thyroxine or ethanol-induced osteoporosis, and hypercalcemia induced by retinoic acid.
